Simon KH SZETO

Research Programmes

1. The use of optical coherence tomography (OCT) biomarkers in predicting treatment outcome of diabetic macular edema (DME)
2. Displacement of massive submacular haemorrhage with subretinal cocktail injection of tissue plasminogen activator, anti-vascular endothelial growth factors and air, an interventional case series
3. The use of OCT biomarkers in predicting treatment outcome of macular edema secondary to retinal vein occlusion
4. Vision threatening diabetic retinopathy study (VTDRS)
5. Application of artificial intelligence (AI) in retinal imaging

Accomplishments

As first author

1. The use of OCT biomarkers in predicting treatment outcome of diabetic macular edema has been published in British Journal of Ophthalmology
2. The use of non-mydriatic ultrawide field fundus photography in the assessment of diabetic retinopathy and diabetic macular edema has been published in British Journal of Ophthalmology

As co-author

1. The use of artificial intelligence in OCT classification system for classification of DME has been published in Diabetes Care
2. The use of OCT angiography in predicting progression of diabetic retinopathy has been published in Ophthalmology

Representative Publications:

(*corresponding author)

1. Szeto SKH, Lai TYY, Vujosevic S, Sun JK, Sadda SVR, Tan G, Sivaprasad S, Wong TY, Cheung CY. Optical Coherence Tomography in the Management of Diabetic Macular Oedema. Prog Retin Eye Res. (In press 2023)
2. Yang DW, Tang ZQ, Tang FY, Szeto SK, Chan J, Yip F, Wong CY, Ran AR, Lai TY, Cheung CY. Clinically relevant factors associated with a binary outcome of diabetic macular ischaemia: an OCTA study. Br J Ophthalmol. 2023 Sep;107(9):1311-1318.
3. Szeto SK, Hui VWK, Tang FY, Yang D, Sun ZH, Mohamed S, Chan CKM, Lai TYY, Cheung C. OCT-based biomarkers for predicting treatment response in eyes with centre-involved diabetic macular oedema treated with anti-VEGF injections: a real-life retina clinic-based study. Br J Ophthalmol. 2023 Apr;107(4):525-533.
4. Szeto SK, Hui VWK, Siu V, Mohamed S, Chan CKM, Cheung CYL, Hsieh YT, Tan CS, Chhablani J, Lai TYY, Ng DS. Recent Advances in Clinical Applications of Imaging in Retinal Diseases. Asia Pac J Ophthalmol (Phila). 2023 Mar-Apr 01;12(2):252-263.
5. Szeto SK*, Mohamed S, Tsang CW, Chan CK. Massive retinal infiltrates as the presenting sign of chronic myeloid leukemia: Clinical and imaging features of leukemic retinopathy. Eur J Ophthalmol. 2023 Jan;33(1):NP55-NP63.
6. Szeto SK*, Mohamed S, Tsang CW, Lai TYY, Hui VWK, Chan CKM. Multimodal imaging features of choroidal metastasis of non-small-cell lung cancer: a case report. Hong Kong J Ophthalmol. 2022 Dec;26(2):98-104
7. Lai TYY, Tang Z, Lai ACW, Szeto SKH, Lai RYK, Cheung CY. Association of Fundus Autofluorescence Abnormalities and Pachydrusen in Central Serous Chorioretinopathy and Polypoidal Choroidal Vasculopathy. J Clin Med. 2022 Sep 11;11(18):5340.
8. Hui VWK, Szeto SKH, Tang F, Yang D, Chen H, Lai TYY, Rong A, Zhang S, Zhao P, Ruamviboonsuk P, Lai CC, Chang A, Das T, Ohji M, Huang SS, Sivaprasad S, Wong TY, Lam DSC, Cheung CY. Optical Coherence Tomography Classification Systems for Diabetic Macular Edema and Their Associations With Visual Outcome and Treatment Responses – An Updated Review. Asia Pac J Ophthalmol (Phila). 2022 Jun 1;11(3):247-257.
9. Lam SC, Szeto SKH, Yuen HKL. Giant Fornix Syndrome: How Much Conjunctiva Should Be Resected? Ophthalmic Plast Reconstr Surg. 2022 Jan-Feb 01;38(1):45-49.
10. Yang D, Sun Z, Shi J, Ran A, Tang F, Tang Z, Lok J, Szeto S, Chan J, Yip F, Zhang L, Meng Q, Rasmussen M, Grauslund J, Cheung CY. A Multitask Deep-learning System for Assessment of Diabetic Macular Ischemia on Optical Coherence Tomography Angiography Images. Retina. 2022 Jan 1;42(1):184-194.
11. Tang F, Luenam P, Ran AR, Quadeer AA, Raman R, Sen P, Khan R, Giridhar A, Haridas S, Iglicki M, Zur D, Loewenstein A, Negri HP, Szeto S, Lam BKY, Tham CC, Sivaprasad S, Mckay M, Cheung CY. Detection of Diabetic Retinopathy from Ultra-Widefield Scanning Laser Ophthalmoscope Images: A Multicenter Deep Learning Analysis. Ophthalmol Retina. 2021 Nov;5(11):1097-1106.
12. Tang F, Wang X, Ran AR, Chan CKM, Ho M, Yip W, Young AL, Lok J, Szeto S, Chan J, Yip F, Wong R, Tang Z, Yang D, Ng DS, Chen LJ, Brelén M, Chu V, Li K, Lai THT, Tan GS, Ting DSW, Huang H, Chen H, Ma JH, Tang S, Leng T, Kakavand S, Mannil SS, Chang RT, Liew G, Gopinath B, Lai TYY, Pang CP, Scanlon PH, Wong TY, Tham CC, Chen H, Heng PA, Cheung CY. A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis. Diabetes Care. 2021 Sep;44(9):2078-2088.
13. Tang Z, Chan MY, Leung WY, Wong HY, Ng CM, Chan VTT, Wong R, Lok J, Szeto S, Chan JCK, Tham CC, Wong TY, Cheung CY. Assessment of retinal neurodegeneration with spectral-domain optical coherence tomography: a systematic review and meta-analysis. Eye (Lond). 2021 May;35(5):1317-1325.
14. Tang FY, Chan EO, Sun Z, Wong R, Lok J, Szeto S, Chan JC, Lam A, Tham CC, Ng DS, Cheung CY. Clinically relevant factors associated with quantitative optical coherence tomography angiography metrics in deep capillary plexus in patients with diabetes. Eye Vis (Lond). 2020 Feb 3;7:7.
15. Sun Z, Tang F, Wong R, Lok J, Szeto SKH, Chan JCK, Chan CKM, Tham CC, Ng DS, Cheung CY. OCT Angiography Metrics Predict Progression of Diabetic Retinopathy and Development of Diabetic Macular Edema: A Prospective Study. Ophthalmology. 2019 Dec;126(12):1675-1684.
16. Szeto SKH, Wong R, Lok J, Tang F, Sun Z, Tso T, Lam TCH, Tham CC, Ng DS, Cheung CY. Non-mydriatic ultrawide field scanning laser ophthalmoscopy compared with dilated fundal examination for assessment of diabetic retinopathy and diabetic macular oedema in Chinese individuals with diabetes mellitus. Br J Ophthalmol. 2019 Sep;103(9):1327-1331.
17. Tang F, Sun Z, Wong R, Lok J, Lam A, Tham CC, Chan CK, Mohamed S, Lam TC, Szeto SK, Ng DS, Cheung CY. Relationship of intercapillary area with visual acuity in diabetes mellitus: an optical coherence tomography angiography study. Br J Ophthalmol. 2018 Jun 4:bjophthalmol-2017-312010.
18. Szeto SK, Chan TC, Wong RL, Ng AL, Li EY, Jhanji V. Prevalence of Ocular Manifestations and Visual Outcomes in Patients With Herpes Zoster Ophthalmicus. Cornea. 2017 Mar;36(3):338-342.

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