Associate Professor

MB ChB (CUHK), MRCSEd, FCOphthHK, FHKAM (Ophthalmology)

Contact :

(852) 3943 5824

Academic Appointments

  • Associate Professor, Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong (CUHK)
  • Clinical Director, Eye Centre, CUHK Medical Centre (CUHKMC)
  • Deputy Director, CUHK Eye Centre (CUHKEC)
  • Head, Orbital and Oculoplastic Surgery Service, New Territories East Cluster (NTEC) Ophthalmology Service
  • Honorary Consultant, CUHKMC, Hong Kong Eye Hospital, Prince of Wales Hospital, Alice Ho Nethersole Hosptial, Queen Mary Hospital, and Grantham Hospital
  • 1st Vice President, Asia Pacific Society of Ophthalmic Plastic and Reconstructive Surgery
  • Secretary, Asia Pacific Society of Ophthalmic Plastic and Reconstructive Surgery
  • Council Member / Education Officer, International Thyroid Eye Disease Society
  • Member, American Society of Ophthalmic Plastic and Reconstructive Surgery
  • Advisory Committee, International society of Dacryology and Dry Eye

Biography

Dr Kelvin KL CHONG′s clinical and research interest focus on oculofacial plastic conditions including thyroid eye disease, orbital tumors, trauma, tearing disorders and minimally invasive eyelid, lacrimal and orbital surgeries.

He graduated at the top of his class in the CUHK Faculty of Medicine (MBChB ) program.  He was awarded the Li Po Chun Charitable Trust Fund Overseas Postgraduate Scholarship to the University of California at Los Angeles (UCLA) and LA Biomedical Institute where he returned later for a 2-year surgical and translational research fellowship.  His awards included the City Lion Club Gold Medal, Action for Vision Eye Foundation Young Researcher of the Year, Achievement Awards from American Academy of Ophthalmology (AAO) and Asia Pacific Academy of Ophthalmology (APAO), best surgical video awards in AAO (2012, 2014) and World Ophthalmology Congress (2018).  He has over 40 SCI indexed peer-reviewed articles and 5 book chapters.

Dr Chong currently serves as the Head of the Orbital and Oculoplastic Division at the Department of Ophthalmology and Visual Science (DOVS) and Prince of Wales Hospital (PWH) and the Associate Director of the CUHK Eye Center.

He is the current President of Hong Kong Society of Ophthalmic Plastic and Reconstructive Surgery (HKSOPRS), First Vice-President of the Asia-Pacific Society of Ophthalmic Plastic and Reconstructive Surgery (APSOPRS) and education officer of the International Thyroid Eye Disease Society (ITEDS). He is recently inducted into the American Society of Ophthalmic Plastic & Reconstructive Surgery (ASOPRS).

Research Areas

  1. Mohs micrographic surgery for periocular tumor (CUHK Direct grant 2007)
  2. Clinical and translational research on thyroid associated orbitopathy (TAO)/ thyroid eye disease (TED) (CUHK Direct grant 2013, 2014, 2015)
  3. Image-guided orbital surgeries (Nethersole Charity Foundation 2012-5)
  4. Endoscopic lacrimal and orbital surgeries (Nethersole Charity Foundation 2015-8)
  5. 3-dimensional printing in orbital fracture repair (Innovation and Technology Fund 2016-8)
  6. Adult stem cells research in Ophthalmology
  7. Laser refractive and laser-assisted cataract surgery
Subspecialty Liaison (Orbital and Oculoplastic Surgery Program) World Ophthalmology Congress 2018 Barcelona (Spain)
Subspecialty Liaison ( Orbital and Oculoplastic Surgery Program) The 33rd Asia-Pacific Academy of Ophthalmology Congress 2018 (Hong Kong)
Subspecialty Liaison ( Orbital and Oculoplastic Surgery Program ) The 32nd Asia-Pacific Academy of Ophthalmology Congress 2017 (Singapore)
Subspecialty Liaison ( Orbital and Oculoplastic Surgery Program ) World Ophthalmology Congress 2016 (Mexico)
Subspecialty Liaison ( Orbital and Oculoplastic Surgery Program ) The 31st Asia-Pacific Academy of Ophthalmology Congress 2016 (Taiwan)
Keynote lecturer Korean Ophthalmological Symposium & Korean Society of Ophthalmic 2015 (South Korea)
Keynote lecturer Plastic and Reconstructive Surgery Symposium 2015

Research Programmes

  1. Multi-disciplinary approach to Thyroid Eye Disease (TED), ImmunoglobulinG4 related disease (IgG4RD) and Dry Eye Disease (DED)
    • Early Detection and Treatment Reduce Severity (EDTRS)
    • Image and immune guided, intelligent and integrated (I2GI2) management
    • Asia-Pacific Consensus, Epidemiology, Education & Empowerment
  2. Trans-disciplinary digital revolution for the next-generation oculoplastic surgeries
    • Image-guided and minimally invasive oculoplastic surgeriesc)
    • Intelligent device: robots, microrobots and non-invasive drug delivery
    • Immersive surgeries and training: 3-dimensional printing and viewing
  3. Inter-disciplinary studies on TED, DED and COVID-19 & eyes
    • Cellular, animal to big data models for therapeutic targeting and screeningc)
    • Immune, genomic and metagenomic (microbiome) biomarkers
    • Intelligent data management (big data) and analysis (deep learning)
  4. Cross-disciplinary research From Eyes to Brain, Body and Behaviour
    • Infrared pupillometry and eye-tracking in brain, body and behaviour changes
    • COVID & eyes″ on transmission, complications and systemic surveillance
    • Sports Ophthalmology: ‶Eyes and hands on medals″

Accomplishments 

  1. The first and the largest-to-date thyroid eye clinic in HK (2010):
    • Hospital Authority Outstanding Staff & Teams Award (2020)
    • Top Surgical Video Award, World Ophthalmology Congress (WOC, 2018)
    • The Endocrine Society′s International Award for Excellence (2011)
    • The first series of endoscopic orbital decompression in HK (2010)
    • The world′s first series of triple combined immunosuppression (2011)
  2. First and largest territory-wide IgG4-related ophthalmic disease (IgG4ROD) cohort
    • Best Poster Award, American Academy of Ophthalmology (2020)
  3. The first use of 3D-printing in orbital fracture repair, Innovation and Technology Fund (2017) Bronze Medal, 48th International Exhibition of Inventions in Geneva (2023)
  4. The world′s first and largest randomized controlled trial on endoscopic dacryocyto-rhinostomy for nasolacrimal duct obstruction with long-term follow-up (2013)
  5. The first and the only-to-date Mohs Micrographic Surgery (2007) in HK with sentinel lymph node biopsy for periocular malignancy (2013)
  6. Established the first multidisciplinary team (neurosurgery, head & neck, plastic surgery, radiology, oncology, pathology) for orbitocraniofacial conditions in HK (2012)
  7. The first use of endoscopic navigation for orbital surgeries in HK (2015)

Representative Publications:

(*corresponding author; **co-first author )

  1. Lai KKH, Wang Y, Pang CP, Chong KKL*. Sirolimus versus mycophenolate mofetil for triple immunosuppression in thyroid eye disease patients with recent-onset intractable diplopia: A prospective comparative case series. Clin Exp Ophthalmol. 2023 Sep 11.
  1. Lai KKH, …, Chen LJ, Tham CC, Pang CP, Chong KKL*. Ocular Surface Evaluation in Immunoglobulin G4-Related Ophthalmic Disease. Am J Ophthalmol. 2023 Aug 5;256:90-96.
  2. Lai KKH, …, Chong KKL*. Efficacy and Safety of 6-Weekly versus 12-Weekly Intravenous Methylprednisolone in Moderate-to-Severe Active Thyroid-Associated Ophthalmopathy. J Clin Med. 2023 May 1;12(9):3244.
  3. Liao X, …, Tham CCY, Pang CP, Chong KKL*. Investigating the Impact of COVID-19 Infection on Dry Eye Parameters. Diagnostics (Basel). 2023 Apr 24;13(9):1524.
  4. Liao X, …, Tham CCY, Pang CP, Chong KKL*. Ocular Surface Changes in Treatment-Naive Thyroid Eye Disease. J Clin Med. 2023 Apr 23;12(9):3066.
  5. Chan R, …, Chong K*. Mohs Surgery for Periocular Basal Cell Carcinoma Without a Mohs Surgeon: The First Series in Hong Kong. Cureus. 2023 Mar 16;15(3):e36235.
  6. Zhang M, Chong KK**, …, Wang Y. Rapamycin improves Graves′ orbitopathy by suppressing CD4+ cytotoxic T lymphocytes. JCI Insight. 2023 Feb 8;8(3):e160377.
  7. Lai KKH, …, Tham CCY, Pang CP, Chong KKL*. Malignancies in Immunoglobulin G4-related ophthalmic disease. Eur J Ophthalmol. 2023 Jan;33(1):171-181.
  8. Lai KKH, …, Tham CCY, Pang CP, Chong KKL*. Treatment outcomes and their determinants of IgG4-related ophthalmic disease: a territory-wide cohort study. Br J Ophthalmol. 2022 Oct 26:bjophthalmol-2021-320936.
  9. Yang H, …, Chong KKL*, Pang CP*, Li Z*. Magnetic micro-driller system for nasolacrimal duct recanalization. IEEE Robotics and Automation Letters. 2022 July; 7(3):7367-7374
  10. Lai KKH, …, Tham CCY, Pang CP, Chong KKL*. Radiological Determinants of Complicated Immunoglobulin G4-Related Ophthalmic Disease: A Territory-Wide Cohort Study. Asia Pac J Ophthalmol (Phila). 2022 Sep 1;11(5):417-424.
  11. Wan KH, …, Tham CCY, …, Pang CP, Chong KKL*. Ocular surface disturbance in patients after acute COVID-19. Clin Exp Ophthalmol. 2022 May;50(4):398-406.
  12. Lai KKH, …, Chong KKL*. Upper Cranial Nerve Involvement and Immunoglobulin G4-Related Optic Neuropathy. Ophthalmology. 2020 May;127(5):699-703.
  13. Chin J,…, Chong KKL*. Comparative study of stenting and ostium packing in Endoscopic Dacryocystorhinostomy for Primary Acquired Nasolacrimal Duct Obstruction. Sci Rep. 2020 Jan 8;10(1):46.
  14. Lai FHP, …, Chong KKL*. Choroidal thickness in thyroid associated orbitopathy. Clin Exp Ophthalmol. 2019 Sep;47(7):918-924.
  15. Wong JSC, …, Chu WK, …, Pang CP, Chong KKL*. Elevated bone morphogenic protein 4 expression implicated in site-specific adipogenesis in thyroid associated orbitopathy. Exp Eye Res. 2019 Apr;181:185-9.
  16. Iao TWU, …, Brelén ME, …, Chong KKL*. Electrophysiological Studies in Thyroid Associated Orbitopathy: A Systematic Review. Sci Rep. 2017 Sep 21;7(1):12108.
  17. Chong KK* et al. Randomized trial on Silicone intubation in Endoscopic Mechanical Dacryocystorhinostomy (SEND) for primary nasolacrimal duct obstruction. Ophthalmology. 2013 Oct;120(10):2139-45.
  18. Khanna D, Chong KK**. Rituximab treatment of patients with severe, corticosteroid-resistant thyroid-associated ophthalmopathy. Ophthalmology. 2010 Jan;117(1):133-139.e2.

 

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