Dr Jingna HE, PhD

Year of graduation: 2019

Supervisors: Dr Wai Kit CHU


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Research Direction

  • Oxidative stress and autophagy in Primary Open Angle Glaucoma (POAG).
  • The role of OPTN mutation in the pathology of POAG.
  • Bacteriological profile of ocular surface flora in conjunctiva and Meibomian gland.

Current Affiliations and Positions

  • Postdoctoral Fellow, Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong

Representative Publications

  1. Zhang, S.D., He, J.N., Niu, T.T., Liu, S.S., Chan, C.Y., Ren, C.Y., Liu, C., Pang, C.P., Qu, Y., Li, R.X., and Wang, H.L., Effectiveness of meibomian gland massage combined with topical levofloxacin against ocular surface flora in patients before penetrating ocular surgery. Ocular Surface, 2018. 16(1): p. 70-76.
  2. He, J.N., Zhang, S.D., Qu, Y., Wang, H.L., Tham, C.C., Pang, C.P., and Chu, W.K., Rapamycin Removes Damaged Mitochondria and Protects Human Trabecular Meshwork (TM-1) Cells from Chronic Oxidative Stress. Molecular Neurobiology, 2019. 56(9): p. 6586-6593.
  3. He, J.N., Lu, S., Chen, L.J., Tam, P.O.S., Zhang, B.N., Leung, C.K.S., Pang, C.P., Tham, C.C.Y., and Chu, W.K., Coding Region Mutation Screening in Optineurin in Chinese Normal-Tension Glaucoma Patients. Disease Markers, 2019. 2019: p. 5820537.
  4. He J.N., CHU W.K., Tham C.C., Pang C.P., Consequences of OPTN mutation in HTM cells. Investigative Ophthalmology & Visual Science. 2020. 61(7):3444.
  5. He, J.N., Chu, W. K., Ma, L., Pang, C. C., & Chen, G. L. Retina Genes in Chinese. In Advances in Vision Research, 2019, Volume II (pp. 177-190). Springer, Singapore.
  6. Zhang, S.D., He, J.N., Niu, T.T., Chan, C.Y., Ren, C.Y., Liu, S.S., Qu, Y., Chong, K.L., Wang, H.L., Tao, J., and Pang, C.P., Bacteriological profile of ocular surface flora in meibomian gland dysfunction. Ocular Surface, 2017. 15(2): p. 242-247.
  7. Li, J., Yip, Y.W.Y., Ren, J., Hui, W.K., He, J.N., Yu, Q.X., Chu, K.O., Ng, T.K., Chan, S.O., Pang, C.P., and Chu, W.K., Green tea catechins alleviate autoimmune symptoms and visual impairment in a murine model for human chronic intraocular inflammation by inhibiting Th17-associated pro-inflammatory gene expression. Scientific Reports, 2019. 9(1): p. 2301.
  8. Zhang, B.N., Wong, T.C.B., Yip, Y.W.Y., Liu, Z., Wang, C., Wong, J.S.C., He, J.N., Chan, T.C.Y., Jhanji, V., Pang, C.P., Zhao, H., and Chu, W.K., A sclerocornea-associated RAD21 variant induces corneal stroma disorganization. Experimental Eye Research, 2019. 185: p. 107687.