Dr NG Siu Chun Danny

Assistant Professor

BSc (Johns Hopkins University), MBBS (HKU), MPH (HKU), FRCS (Edin), FCOphth (HK), FHKAM (Ophth)

Contact :

(852) 3943 5824

Request An Appointment :

(852) 3943 5886

Academic Appointments

  • Assistant Professor, Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong
  • Deputy Director, Ophthalmic Microsurgical Training Centre

Biography

Dr Danny Ng obtained his bachelor’s degree in Biomedical Engineering from Johns Hopkins University where he graduated with departmental honors. He received his medical degree and Master of Public Health from the Faculty of Medicine, University of Hong Kong. Dr Ng is a Fellow of the Royal College of Surgeons of Edinburgh in Ophthalmology and the College of Ophthalmologists of Hong Kong.

Dr Ng has been awarded the Johns Hopkins Provost’s Research Award for his neurogenetics research in X-linked adrenoleukodystrophy at the Kennedy Krieger Institute. He has also researched microglia activation in retinal vascular disease with Prof. Mark Tso at the Wilmer Eye Institute. Clinically, Dr Ng has developed minimally invasive and scarless techniques in oculoplastic surgery. He has studied the treatment effects on choroidal neovascularization in pathological myopia and age-related macular degeneration, and is actively involved in clinical drug trials. He has more than 20 publications, co-authored 2 book chapters and delivered over 25 presentations at local and international scientific meetings.

Dr Ng is actively involved in medical education locally and overseas. He organized microsurgical training for ophthalmic trainees and was invited by medical students to present in health exhibitions. He has supervised undergraduate research students in projects that were presented in international scientific meetings.

Research Areas

  1. Medical therapies in age-related macular degeneration polypoidal choroidal vasculopathy, central serous chorioretinopathy and pathologic myopia
  2. Choroidal imaging and its association with ocular and systemic diseases
  3. Diabetic retinopathy and maculopathy
  4. Ocular trauma
Glaucoma Subspecialty Liaison and Session Chairs World Ophthalmology Congress 2018 (Spain)
Coordinator/Secretary and Session Chairs (Glaucoma Subspecialty program) The 33rd Asia-Pacific Academy of Ophthalmology Congress 2018 (Hong Kong)
International Advisory Committee The Association for Research in Vision and Ophthalmology-Asia 2017 (Australia)

Research Programmes

  1. The clinical safety and efficacy of pharmaceutical and laser interventions in medical retina diseases, including age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV) and central serous chorioretinopathy (CSC).
  2. Imaging techniques of the choroid and its morphological changes.
  3. Imaging studies and clinical interventions in pathologic myopia.
  4. Phenotype-genotype studies of the role of angiogenesis in medical retina diseases and aging.
  5. Construct validity of innovative technologies in simulated ophthalmic microsurgical training.

Results of Note

  1. Dr Ng and his research team at CUHK used the latest imaging technology in optical coherence tomography (OCT) for non-invasive scanning of the choroid, the deep layer underlying the retina, to study the morphological changes of blood vessels in AMD and PCV patients.
  2. Characterization of the structural changes of the choroid in association with disease phenotypes and treatment responses that are imperative to the optimisation and individualization of novel medical treatments.
  3. The application of OCT-angiography to study choroidal neovascularisation and chorioretinal atrophy in pathologic myopia.
  4. Identification of the role angiopoietin-2, a cytokine associated with angiogenesis, in AMD and PCV patients.
  5. Validation of a computer-generated virtual reality training environment in cataract extraction surgery, in terms of increasing the training efficiency and improving patient safety outcomes.

Representative Publications:

  1. Ng DS, Bakthavatsalam M, Lai FH, Cheung CY, Cheung GC, Tang FY, Tsang CW, Lai TY, Wong TY, Brelén ME. Classification of Exudative Age-Related Macular Degeneration With Pachyvessels on En Face Swept-Source Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1054-1062.
  2. Ma L, Brelen ME, Tsujikawa M, Chen H, Chu WK, Lai TY, Ng DS, Sayanagi K, Hara C, Hashida N, Chan VC, Tam PO, Young AL, Chen W, Nishida K, Pang CP, Chen LJ. Identification of ANGPT2 as a New Gene for Neovascular Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy in the Chinese and Japanese Populations. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1076-1083.
  3. Bakthavatsalam M, Ng DS, Lai FH, Tang FY, Brelén ME, Tsang CW, Lai TY, Cheung CY. Choroidal structures in polypoidal choroidal vasculopathy, neovascular age-related maculopathy, and healthy eyes determined by binarization of swept source optical coherence tomographic images. Graefes Arch Clin Exp Ophthalmol. 2017 May;255(5):935-943.
  4. Fan H, Ma H, Gao R, Ng DS, Cheung CY, Li S, Wu D, Tang S. Associated factors for visibility and width of retrobulbar subarachnoid space on sweptsource optical coherence tomography in high myopia. Sci Rep. 2016 Nov 9;6:36723.
  5. Huang Y, Huang W, Ng DS, Duan A. Risk factors for development of macular hole retinal detachment after pars plana vitrectomy for pathologic myopic foveoschisis. Retina. 2017 Jun;37(6):1049-1054.
  6. Lai FH, Ng DS, Bakthavatsalam M, Chan VC, Young AL, Luk FO, Tsang CW, Brelén ME. A Multicenter Study on the Long-term Outcomes of Half-dose Photodynamic Therapy in Chronic Central Serous Chorioretinopathy. Am J Ophthalmol. 2016 Oct;170:91-99.
  7. Ng DS, Lai TY, Ng TK, Pang CP. Genetics of Bietti Crystalline Dystrophy. Asia Pac J Ophthalmol (Phila). 2016 Jul-Aug;5(4):245-52.
  8. Ng DS, Cheung CY, Luk FO, Mohamed S, Brelen ME, Yam JC, Tsang CW, Lai TY. Advances of optical coherence tomography in myopia and pathologic myopia. Eye (Lond). 2016 Jul; 30(7): 901-16.
  9. Ng DS, Kwok AK, Tong JM, Chan CW, Li WW. Bevacizumab for neovascular age-related macular degeneration in Chinese patients in a clinical setting. Int J Ophthalmol. 2016 Mar 18; 9(3):424-30.
  10. Ng DS, Kwok AK, Tong JM, Chan CW, Li WW. Factors influencing need for retreatment and longterm visual outcome after intravitreal bevacizumab for myopic choroidal neovascularization. Retina. 2015 Dec;35(12):2457-68.

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