Half dose photodynamic therapy shows good longterm outcomes for patients with central serous chorioretinopathy
Central serous chorioretinopathy (CSCR) is characterized by detachments of the neurosensory retina. Chronic CSCR, if left untreated, can cause irreversible long-term vision loss. Photodynamic therapy (PDT) has been reported as an effective treatment option for CSCR. However, PDT has the potential of causing complications such as scarring or subretinal haemorrhage.. Therefore, more recently, it has become popular to use lower dose PDT to minimize the side-effects. Dr Mårten Brelén from the Department of Ophthalmology and Visual Sciences of CUHK found that treating chronic CSCR by using half-dose PDT can achieve good final visual acuity outcomes in the long-term . This study also found that patients with chronic CSCR are more likely to have better treatment outcomes if treated early before any significant visual deterioration.
1. Lai,F.H.P., et.al. A Multicenter Study on the Long-term Outcomes of Half-dose Photodynamic Therapy in Chronic Central Serous Chorioretinopathy. American Journal of Ophthalmology. 170, pages 91-99.