Ophthalmic Research – TANG Shumin

TANG Shumin

 

Qualifications:

  • MPhil, Ophthalmology and Visual Sciences, The Chinese University of Hong Kong
  • Bachelor, Ophthalmology and Optometry, Wenzhou Medical University

Research Areas:

  1. Epidemiology of pediatric eye diseases – Hong Kong Children Eye Study (HKCES)
  2. Identification of risk factors for myopia
  3. Meta-analysis on risk factors of pediatric eye diseases

Supervisors:

Publications:

  1. Au, S. C.*, S. M. Tang*, S. S. Rong, L. J. Chen and J. C. Yam (2015). “Association between hyperglycemia and retinopathy of prematurity: a systemic review and meta-analysis.” Sci Rep 5: 9091.
  2. Chan, P. Y.*, S. M. Tang*, S. C. Au, S. S. Rong, H. H. Lau, S. T. Ko, D. S. Ng, L. J. Chen and J. C. Yam (2016). “Association of Gestational Hypertensive Disorders with Retinopathy of prematurity: A Systematic Review and Meta-analysis.” Sci Rep 6: 30732.
  3. Ma, L.*, S. M. Tang*, S. S. Rong, H. Chen, A. L. Young, G. Kumaramanickavel, C. P. Pang and L. J. Chen (2015). “Association of PEDF polymorphisms with age-related macular degeneration and polypoidal choroidal vasculopathy: a systematic review and meta-analysis.” Sci Rep 5: 9497.
  4. Rong, S. S., F. Y. Tang, W. K. Chu, L. Ma, J. C. Yam, S. M. Tang, J. Li, H. Gu, A. L. Young, C. C. Tham, C. P. Pang and L. J. Chen (2016). “Genetic Associations of Primary Angle-Closure Disease: A Systematic Review and Meta-analysis.” Ophthalmology 123(6): 1211-1221.
  5. Tang, S. M.*, S. S. Rong*, A. L. Young, P. O. Tam, C. P. Pang and L. J. Chen (2014). “PAX6 gene associated with high myopia: a meta-analysis.” Optom Vis Sci 91(4): 419-429.
  6. Tang, S. M.*, R. Y. Chan*, S. Bin Lin*, S. S. Rong, H. H. Lau, W. W. Lau, W. W. Yip, L. J. Chen, S. T. Ko and J. C. Yam (2016). “Refractive Errors and Concomitant Strabismus: A Systematic Review and Meta-analysis.” Sci Rep 6: 35177.

 

Research Highlights:

(1) Epidemiology of pediatric eye diseases – Hong Kong Children Eye Study (HKCES)

Childhood visual impairment is a global public health issue, because it not only affects children’s vision and his subsequent education, employment and future social prospects, but also increases economic burden to their families and the whole society. The uncorrected and under-corrected refractive errors, especially myopia, were one of the major causes of visual impairment in children. Furthermore, high myopia can lead to potential blinding complications including myopic macular degeneration, choroidal neovascularization, retinal detachment and glaucoma etc. Therefore, myopia is an important public health issue worldwide. With the change of lifestyles and environments, the prevalence of myopia has increased rapidly in recent decades. The increasing prevalence and severe degree of myopia would give rise to a heavier burden to both individuals and society in the near future. Therefore, it is of utmost importance to identify the reasons for the increasing myopia prevalence, and then retard the onset and progression of myopia.

Aside from myopia, other pediatric ocular diseases like amblyopia and strabismus also affects children’s vision. The prevalence of amblyopia was ranged from 1.3% to 7.7% in children aged 5-15 years and the prevalence was various across different ethnic groups. Strabismus has the prevalence ranging from 2.3% to 6% in children. Allergic eye disease is another very common ocular disorder in children, strongly associated with allergic rhinitis as well as other atopy such as eczema, asthma and atopic dermatitis. Identifying the risk factors for these pediatric eye diseases as well as their prevalence has important implication for health care resources allocation and the diseases prevention.

Therefore, we aim
1) to determine the prevalence of all types of childhood eye diseases in Hong Kong, including myopia, strabismus, amblyopia, and allergic eye diseases;
2) to identify the environmental and genetic determinants of childhood diseases based on comprehensive examination and questionnaires;
3) to determine diseases incidence and progression after longitudinal follow-up every 2 years.