Medical Retina & Uveitis Fellowship Programme

CUHK-HKEH-PWH International Ophthalmology Fellowship
Medical Retina and Uveitis

Medical Retina and Uveitis Programme Director:

Dr Mårten BRELÉN

Dr Mårten BRELÉN

Assistant Professor

Faculty:

Dr Carmen KM Chan

Dr Carmen KM Chan

Clinical Assistant Professor (Honorary), CUHK
Consultant, HKEH

Dr CW Tsang

Dr CW Tsang

Clinical Assistant Professor (Honorary), CUHK
Consultant, HKEH

Introduction

The Medical Retina and Uveitis Service at the Hong Kong Eye Hospital provides high quality subspecialty care in the diagnosis and treatment of Medical Retina diseases and Uveitis for patients in Hong Kong. Our clinic serves more than 100 patients every week. Besides providing high quality patient care, the Medical Retina and Uveitis service has a strong track record in research. During the fellowship, fellows will actively participate in all clinical services and various research projects.

Training Programme for fellows

Clinical Attachment for Medical Retina and Uveitis:
  • 3 outpatient clinics per week including Medical Retina Clinic, Uveitis Clinic, and Diabetic Macular Edema clinic
  • 1 session of electrophysiology per week
  • 1 session of intravitreal injections and photodynamic therapy per week
  • 2 sessions of laser clinic per month.
Ongoing Research Activities in Medical Retina and Uveitis:
  • Genetic studies in age-related macular degeneration, hereditary retinal diseases and Uveitis
  • Pharmacological treatment for age-related macular degeneration, diabetic macular edema and other retinal diseases including anti-VEGF and photodynamic therapy
  • Clinical application of visual electrophysiology including multifocal ERG, full-field ERG, pattern ERG, and VEP
  • Evaluation of macular diseases with fluorescein angiography, indocyanine green angiography and optical coherence tomography.
Major equipments for Medical Retina and Uveitis
  • Topcon® flash fluorescein and indocyanine green angiography fundus cameras
  • Heidelberg® HRA Spectralis system
  • EDI® VERISTM multifocal electroretinography system
  • Diagnosys® Espion E2 electrophysiology system
  • Optical coherence tomography
  • Multi-wavelength argon laser

Selected Recent Publications from Medical Retina and Uveitis Service

  1. Association of CFH and SERPING1 polymorphisms with anterior uveitis.
    Yang MM, Lai TY, Tam PO, Chiang SW, Ng TK, Rong SS, Pang CP.
    Br J Ophthalmol. 2013 Nov;97(11):1475-80. [PubMed Abstract]
  2. THE ROLES OF GENETIC FACTORS IN UVEITIS AND THEIR CLINICAL SIGNIFICANCE.
    Yang MM, Lai TY, Luk FO, Pang CP.
    Retina. 2013 Jul 30. [Epub ahead of print] [PubMed Abstract]
  3. Contribution of SNRNP200 sequence variations to retinitis pigmentosa.
    Zhang X, Lai TY, Chiang SW, Tam PO, Liu DT, Chan CK, Pang CP, Zhao C, Chen LJ.
    Eye (Lond). 2013 Oct;27(10):1204-13. [PubMed Abstract]
  4. Choroidal thickness measurement in myopic eyes by enhanced depth optical coherence tomography.
    Ho M, Liu DT, Chan VC, Lam DS.
    Ophthalmology. 2013 Sep;120(9):1909-14. [PubMed Abstract]
  5. Directing adult human periodontal ligament-derived stem cells to retinal fate.
    Huang L, Liang J, Geng Y, Tsang WM, Yao X, Jhanji V, Zhang M, Cheung HS, Pang CP, Yam GH.
    Invest Ophthalmol Vis Sci. 2013 Jun 6;54(6):3965-74. [PubMed Abstract]
  6. Clinical characteristics of intermediate uveitis in Chinese patients.
    Chan CK, Wu ZH, Luk FO, Liu DT, Fan AH, Lee VY, Lai TY.
    Ocul Immunol Inflamm. 2013;21(1):71-6. [PubMed Abstract]
  7. Associations of the C2-CFB-RDBP-SKIV2L locus with age-related macular degeneration and polypoidal choroidal vasculopathy.
    Liu K, Chen LJ, Tam PO, Shi Y, Lai TY, Liu DT, Chiang SW, Yang M, Yang Z, Pang CP.
    Ophthalmology. 2013 Apr;120(4):837-43 [PubMed Abstract]
  8. Tracking retinal microgliosis in models of retinal ganglion cell damage.
    Liu S, Li ZW, Weinreb RN, Xu G, Lindsey JD, Ye C, Yung WH, Pang CP, Lam DS, Leung CK.
    Invest Ophthalmol Vis Sci. 2012 Sep 14;53(10):6254-62 [PubMed Abstract]
  9. Complement factor H and interleukin gene polymorphisms in patients with non-infectious intermediate and posterior uveitis.
    Yang MM, Lai TY, Tam PO, Chiang SW, Chan CK, Luk FO, Ng TK, Pang CP.
    Mol Vis. 2012;18:1865-72. [PubMed Abstract]
  10. Long-Term Follow-Up of Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization due to Choroidal Osteoma.
    H Y Wu Z, Y Y Wong M, Y Y Lai T.
    Case Rep Ophthalmol. 2012 May;3(2):200-4 [PubMed Abstract]
  11. Association of C2 and CFB polymorphisms with anterior uveitis.
    Yang MM, Lai TY, Tam PO, Chiang SW, Ng TK, Liu K, Pang CP.
    Invest Ophthalmol Vis Sci. 2012 Jul 27;53(8):4969-74. [PubMed Abstract]
  12. Long-term outcome of intravitreal anti-vascular endothelial growth factor therapy with bevacizumab or ranibizumab as primary treatment for subfoveal myopic choroidal neovascularization.
    Lai TY, Luk FO, Lee GK, Lam DS.
    Eye (Lond). 2012 Jul;26(7):1004-11. [PubMed Abstract]
  13. Differentiation of exudative age-related macular degeneration and polypoidal choroidal vasculopathy in the ARMS2/HTRA1 locus.
    Liang XY, Lai TY, Liu DT, Fan AH, Chen LJ, Tam PO, Chiang SW, Ng TK, Lam DS, Pang CP.
    Invest Ophthalmol Vis Sci. 2012 May 31;53(6):3175-82. [PubMed Abstract]
  14. Combined high-dose sub-tenon triamcinolone, intravitreal bevacizumab, and laser photocoagulation for refractory diabetic macular edema: a pilot study.
    Chan CK, Lai TY, Mohamed S, Lee VY, Liu DT, Li CL, Lam DS.
    Retina. 2012 Apr;32(4):672-8. [PubMed Abstract]
  15. Review of Clinical Features, Microbiological Spectrum, and Treatment Outcomes of Endogenous Endophthalmitis over an 8-Year Period.
    Wu ZH, Chan RP, Luk FO, Liu DT, Chan CK, Lam DS, Lai TY.
    J Ophthalmol. 2012;2012:265078. [PubMed Abstract]
  16. CFH 184G as a genetic risk marker for anterior uveitis in Chinese females.
    Yang MM, Lai TY, Tam PO, Chiang SW, Chan CK, Luk FO, Ng TK, Pang CP.
    Mol Vis. 2011;17:2655-64. [PubMed Abstract]
  17. Improvement in multifocal electroretinography after half-dose verteporfin photodynamic therapy for central serous chorioretinopathy: a randomized placebo-controlled trial.
    Wu ZH, Lai RY, Yip YW, Chan WM, Lam DS, Lai TY.
    Retina. 2011 Jul-Aug;31(7):1378-86. [PubMed Abstract]
  18. Intravitreal ranibizumab with or without photodynamic therapy for the treatment of symptomatic polypoidal choroidal vasculopathy.
    Lai TY, Lee GK, Luk FO, Lam DS.
    Retina. 2011 Sep;31(8):1581-8. [PubMed Abstract]
  19. Risk factors for recurrence of serous macular detachment in untreated patients with central serous chorioretinopathy.
    Fok AC, Chan PP, Lam DS, Lai TY.
    Ophthalmic Res. 2011;46(3):160-3. [PubMed Abstract]

Instruction Course Presentations by Faculty at Major International Scientific Conferences

  1. Lai TY, Cheung GC, Fok AC, Fong KC, Lee WK, Luk FO, Iida T, Yu SY
    Diagnosis and Treatment of Central Serous Chorioretinopathy
    2012 Annual Meeting of the American Academy of Ophthalmology (AAO), Chicago, USA.
  2. Lai TY, Lam DS, Lee WK, Mathur R, Luk FO
    Diagnosis and Treatment of Polypoidal Choroidal Vasculopathy (PCV)
    2010 Annual Meeting of the American Academy of Ophthalmology (AAO), Chicago, USA.
  3. Lai TY, Luk FO, Mathur R, Lam DSC
    Diagnosis and Treatment of Polypoidal Choroidal Vasculopathy (PCV)
    2009 Annual Meeting of the American Academy of Ophthalmology (AAO), San Francisco, USA.