Staff Profile – Dr CHEUNG Yim Lui Carol 張艷蕾助理教授


Dr CHEUNG Yim Lui Carol 張艷蕾助理教授

BSc (HKU), MPhil (HKU), PhD (Bham)

Assistant Professor, Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong

Office tel.: (852) 3943 0791
Fax no.: (852) 2715 9490


Dr Cheung’s main research interest is “imaging of the eye”, based on the concept that the eyes are the “window” to the human circulation and nervous systems. Changes in the retinal blood vessels and the optic nerve mirror parallel changes in the brain and other organs in the body and can now be imaged using new technology easily. She has conducted a number of major studies testing the validity of different automated computer programs to perform objective and quantitative assessment of a new class of retinal vascular and optic nerve parameters for evaluation of diabetic retinopathy, glaucoma, Alzheimer’s disease and stroke. The findings of these studies have impacted on understanding of major eye diseases and brain diseases, leading to the development of a more targeted and effective screening strategy using state-of-the-art ocular imaging technology for prevention of blindness and early detection of brain diseases, which has immense potential to lead to impactful benefits to both science and society.

Dr Cheung is editorial board member of Journal of Alzheimer’s Disease and Hypertension Research. She is also a regular reviewer for more than 15 top ranking journals including Ophthalmology, Investigative Ophthalmology & Visual Science, JAMA Ophthalmology, American Journal of Ophthalmology, Alzheimer’s and Dementia, IEEE Transactions on Medical Imaging and PLoS one. She has served as reviewer for international grant funding agencies. She is a council board member and treasurer of Asia Pacific Tele-Ophthalmology Society.

Dr Cheung has authored more than 150 original research articles and 14 review articles in SCI international indexed peer reviewed journals, and 6 book chapters.

Research Areas

  1. Using ocular imaging technology to study human circulation and nervous systems, and link with eye, brain and cardiovascular diseases, in particular, diabetic retinopathy, glaucoma, Alzheimer’s disease and stroke

Representative Publications:

  1. Cheung CY, Ikram MK, Chen C, Wong TY. Imaging Retina to Study Dementia and Stroke. Prog Retin Eye Res. (In Press 2017).
  2. Cheung CY, Ikram MK, Klein R, Wong TY. The clinical implications of recent studies on the structure and function of the retinal microvasculature in diabetes. Diabetologia. 2015 May;58(5):871-85.
  3. Cheung CY, Ong YT, Hilal S, et al. Retinal Ganglion Cell Analysis Using High-Definition Optical Coherence Tomography in Patients with Mild Cognitive Impairment and Alzheimer’s Disease. Journal of Alzheimer’s Disease. 2015;45(1):45-56.
  4. Cheung CY, Ong YT, Ikram MK, Ong SY, Li X, Catindig JAS, Venketasubramanian N, Yap P, Seow D, Chen CP, Wong TY. Microvascular network alterations in the retina of patients with Alzheimer’s Disease. Alzheimers Dement. 2014 Mar;10(2):135-42.
  5. Cheung CY, Tay WT, Ikram MK, Ong YT, De Silva DA, Chow KY, Wong TY. Retinal Microvascular Changes and Risk of Stroke: The Singapore Malay Eye Study. Stroke. 2013 Sep;44(9):2402-2408
  6. Cheung CY, Ikram MK, Sabanayagam C, Wong TY. The Retinal Microvasculature as a Model to Study the Manifestations of Hypertension. Hypertension. 2012 Nov;60(5):1094-103.
  7. Cheung CY, Thomas GN, Tay W, et al. Retinal Vascular Fractal Dimension and its Relationship with Cardiovascular and Ocular Risk Factors. American Journal of Ophthalmology. 2012 Oct;154(4):663-674.e1.
  8. Cheung CY, Zheng YF, Hsu W, et al. Retinal Vascular Tortuosity, Blood Pressure and Cardiovascular Risk Factors. Ophthalmology. 2011 May;118(5):812-8.
  9. Cheung CY, Wong TY, Lamoureux EL, et al. C-reactive Protein and Retinal Microvascular Caliber in a Multi-Ethnic Asian Population. American Journal of Epidemiology. 2010; 171(2):206-213.
  10. Cheung CY, Leung CK, Lin DS, et al. Relationship between Retinal Nerve Fiber Layer Measurement and Signal Strength in OCT. Ophthalmology. 2008 Aug;115(8):1347-51, 1351.e1-2.